Main Street is the second area Shantae visits in Half-Genie Hero. It is part of Scuttle Town and it is a different place than Scuttle Town Square, where the NPCs usually wander about. Shantae first confronts her arch rival, Risky Boots, here and fights P.O.O.P. T.O.O.T. The monkey transformation can be unlocked here.
Risky and her Tinkerbats attack Main Street after stealing Mimic's blueprints for the Dynamo. Shantae confronts Risky and fights her latest contraption and ultimately prevails. She recovers the blueprints and returns them to her Uncle only to be fired by the mayor for allowing Main Street to suffer a lot of collateral damage. Shantae returns to Main Street to help the Chef Girl.